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The Molecular Immunology Lab (Bortoluci Lab), coordinated by Prof. Dr. Karina Ramalho Bortoluci, is mainly focused on the study of intracellular pathways involved on the activation and effector mechanisms mediated by inflammasomes to the control of infections.


Using assays based on molecular and cellular biology, genetics, and biochemistry, we investigate how the activation of those platforms can contribute for the control of infections caused by intracellular pathogens, such as Salmonella typhimurium, Trypanosoma cruzi, Toxoplasma gondii and Zika virus by cells from Innate Immune System and glial cells from Central Nervous System.

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